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GW 275175X
CAS No. 217950-62-4
GW 275175X ( GW275175X )
产品货号. M13479 CAS No. 217950-62-4
GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称GW 275175X
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation.
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产品描述GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation; shows antiviral efficacy against AD169 laboratory strain in DNA hybridization assays with IC50 of 0.7 uM, against 10 clinically relevant HCMV isolates with IC50 of 0.16-2.21 uM, and little or no activity against HSV-1, HSV-2 and varicella zoster virus; inhibits viral DNA maturation in a dose-dependent fashion.
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同义词GW275175X
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通路Microbiology/Virology
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靶点CMV
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受体CMV
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研究领域——
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适应症——
化学信息
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CAS Number217950-62-4
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分子量398.03
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分子式C12H11BrCl2N2O4
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称2-Bromo-5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Williams SL, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2186-92.
2. Underwood MR, et al. Antimicrob Agents Chemother. 2004 May;48(5):1647-51.
2. Underwood MR, et al. Antimicrob Agents Chemother. 2004 May;48(5):1647-51.
产品手册
关联产品
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Brincidofovir (CMX 001;Cidofovir HDP) is a lipid conjugate of the acyclic nucleotide phosphonate.
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BDCRB
BDCRB (GW 275175) is a potent and selective inhibitor of human CMV replication by blocking the processing and maturation of viral DNA.
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CEF20
CEF20, a CEF control peptide pool, is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).
